“SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”

  • Antony Madhuri Bedadala assistant professor in physiology
  • Anthony David M PROFESSOR AND HOD IN PHYSIOLOGY

Abstract

ABSTRACT:

Introduction: Heat stress is a major health burden with potential health out-comes. Oxidative stress is a metabolic dysfunction that carries oxidative damage of cells and tissues. Zinc is a co-factor against oxidative stress. Aim: The present study was done to evaluate the Supplementation of zinc in acute and chronic heat stress on antioxidant changes in wistar albino rats. Methodology: 36 Wistar albino rats were selected for the study. They were divided into 2 Groups. Group A was acutely and Group B was chronically heat stressed rats and both were zinc pretreated. The Enzymatic and Non enzyme activity in them were estimated.

Results: After acute and chronic heat stress, i) there was a significant increase (P <0.001) in lipid peroxidation activity. ii) Enzymatic and Non-enzymatic antioxidants were reduced (P < 0.001) iii) Rats pretreated with zinc showed a decrease (P< 0.001) in lipid peroxidation and increase (P < 0.001) in enzymatic antioxidants (P < 0.001) and Non enzymatic antioxidants.

Key Words: antioxidants, heat stress, wistar albino rats

Published
2020-02-23
How to Cite
Bedadala, A. M., & M, A. D. (2020). “SUPPLEMENTATION OF ZINC IN ACUTE AND CHRONIC HEAT STRESS ON ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS”. International Journal of Current Research in Physiology and Pharmacology (IJCRPP), 4(1), 14-16. https://doi.org/10.31878/ijcrpp.2020.41.04
Section
Research Articles