International Journal of Current Research in Physiology and Pharmacology 2024-03-11T17:25:14+00:00 Editor In Chief Open Journal Systems <p><strong>eISSN: 2523-6709, </strong><strong>pISSN: 2523-6695.</strong></p> <p style="text-align: left;">(Logos are embedded with links)</p> <hr /> <p style="text-align: left;"><a href=";refid=dcrecen" target="_blank" rel="noopener"><img src="" alt="" /></a> <a href=";publication=International+Journal+of+Clinical+and+Biomedical+Research&amp;publisher_str=Sumathi+Publications&amp;type=Journal+Article" target="_blank" rel="noopener"><img src="" alt="" /></a> <a title="IJCRPP" href=";as_sdt=0%2C5&amp;;oq=site" target="_blank" rel="noopener"><img src="" alt="" /></a> <a href=";qt=results_page" target="_blank" rel="noopener"><img src="" alt="" /></a> <a href="" target="_blank" rel="noopener"><img src="" alt="" /></a> <a href=";la=en" target="_blank" rel="noopener"><img src="" alt="" /></a></p> <hr /> <div class="flex-1 overflow-hidden"> <div class="react-scroll-to-bottom--css-ixafv-79elbk h-full"> <div class="react-scroll-to-bottom--css-ixafv-1n7m0yu"> <div class="flex flex-col pb-9 text-sm"> <div class="w-full text-token-text-primary" data-testid="conversation-turn-5"> <div class="px-4 py-2 justify-center text-base md:gap-6 m-auto"> <div class="flex flex-1 text-base mx-auto gap-3 md:px-5 lg:px-1 xl:px-5 md:max-w-3xl lg:max-w-[40rem] xl:max-w-[48rem] group final-completion"> <div class="relative flex w-full flex-col lg:w-[calc(100%-115px)] agent-turn"> <div class="flex-col gap-1 md:gap-3"> <div class="flex flex-grow flex-col max-w-full"> <div class="min-h-[20px] text-message flex flex-col items-start gap-3 whitespace-pre-wrap break-words [.text-message+&amp;]:mt-5 overflow-x-auto" data-message-author-role="assistant" data-message-id="465262a5-c138-4c1b-bbee-aac3b084ef7d"> <div class="markdown prose w-full break-words dark:prose-invert dark"> <p>The International Journal of Current Research in Physiology and Pharmacology (IJCRPP) serves as a platform for scientists in Health Sciences. This open-access, online and print journal is peer-reviewed and primarily focuses on Physiology, Pharmacology, and Clinical Medicine research and applications.</p> <p>Submission Guidelines:</p> <ul> <li>Articles must be in technical English, appropriate for scientific publication.</li> <li>Submissions should be original works, unpublished elsewhere, and not under consideration by other journals.</li> <li>All submissions undergo a peer-review process.</li> <li>Manuscript receipt is acknowledged via email.</li> <li>Review process aims to be completed within 3 weeks, with outcomes communicated to the corresponding author.</li> <li>Submissions are accepted electronically through the journal's website.</li> <li>The Editorial Board is committed to ensuring the journal's quality, and will index it in various bodies, with updates available on the website.</li> </ul> <p>Types of Manuscripts Accepted:</p> <ul> <li>Original research articles</li> <li>Reviews</li> <li>Case reports</li> <li>Short communications</li> <li>Letters to the editor</li> <li>Discussion papers</li> <li>Clinical Experience</li> <li>Clinicopathological correlation</li> <li>Book reviews</li> <li>"How to do it" articles on new methods or procedures</li> </ul> <p>Aims and Critical Objectives:</p> <ul> <li>To inspire new research ideas and encourage practical research application.</li> <li>Upholding the highest editorial integrity standards.</li> <li>Enhancing international health, healthcare, and health education through quality medical care, disease prevention, and research.</li> <li>Publishing significant, well-documented, peer-reviewed articles on basic medical sciences.</li> <li>Providing continuing education in basic science to physicians for better clinical decisions.</li> <li>Keeping doctors informed on various basic medical science aspects, including health education developments.</li> <li>Adhering to the highest ethical standards in medical journalism, ensuring the publication is timely, credible, and engaging.</li> </ul> <p>For further information, contact the Editor or the Journal Office via email.</p> <p>We eagerly await your submissions and hope you consider IJCRPP for your next manuscript.</p> <p>Kind Regards, <br />IJCRPP Editorial Team.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> Formulation and evaluation of herbal paediatric edible jelly of Breynia vitis-idea for helminthic infections 2024-03-11T17:24:54+00:00 Gopikrishna U V Fmith Celvia Miranda Poojary Avirat Vishwanat Swasthika S Vaishnavi V Krishna maucgw7s@GMAIL.COM Vanditha Vijetha AR Shabaraya <p><strong>Aim and Background:</strong> This study delves into the exploration of natural anthelmintics to address helminthiasis, a widespread infectious disease caused by parasitic worms. Leveraging the historical use of plants in phytotherapy, the research focuses on the ethanolic extract of leaves of <em>Breynia vitis-idaea</em> for its potential anthelmintic properties. <strong>Methodology:</strong> The investigation involves phytochemical screening, earthworm bioassays, and the formulation of a child-friendly herbal jelly. <strong>Result: </strong>The study reveals promising anthelmintic efficacy in ethanolic extract of leaves of <em>Breynia vitis-idaea</em>, particularly at concentrations exceeding 40 mg/mL. The formulated herbal jelly, with Batch F3 exhibiting the desired attributes, offers an appealing solution for parasitic infections in children. The dark green jelly, with a pleasant odor and thick consistency, proves to be a viable alternative to traditional anthelmintic drugs. <strong>Conclusion:</strong> The study underscores the global shift towards herbal remedies, driven by their natural origin and minimal side effects. In regions with limited access to modern healthcare, the reliance on traditional practitioners and medicinal plants becomes crucial, emphasizing the need to integrate traditional wisdom with scientific validation. As the world faces evolving health challenges, embracing and further exploring the potential of herbal interventions is imperative for resilient and sustainable healthcare systems. The results of this study add to the growing body of evidence that herbal alternatives to conventional anthelmintic drugs are better, especially when it comes to genetic resistance. The study also supports using herbal remedies in healthcare.</p> <p><strong data-id="_bold-13">Keywords: </strong><em data-id="_italic-4">Breynia vitis-idaea</em>, Anthelmintic activity, Helminthiasis, Jelly.</p> 2024-03-11T00:00:00+00:00 Copyright (c) 2024 Gopikrishna U V, Fmith Celvia Miranda, Poojary Avirat Vishwanat , Swasthika S, Vaishnavi V Krishna, Vanditha, Vijetha, AR Shabaraya Formulation and evaluation of herbal face pack for healthy skincare 2024-03-11T17:21:53+00:00 Navaneeth Krishna B Gopikrishna U V Prarthan K N Subrahmanya Pradeep P Shreesha Shetty Kavyashree S AR SHABARAYA <p><strong>Aim and Background:</strong> This research investigates the formulation and assessment of a herbal face pack, integrating historical insights into plant-based skincare remedies. <strong>Methodology:</strong> Comprising ingredients like neem, multani mitti, turmeric, aloe vera, papaya, liquorice, and rose water, the face pack is designed to enhance skin health and radiance. The study meticulously details the preparation process, emphasizing the incorporation of traditional practices within modern skincare approaches. Comprehensive evaluation encompasses organoleptic, physicochemical, rheological, irritancy, and stability analyses. <strong>Result:</strong> The outcomes affirm that the face pack has commendable attributes, including a pleasing fragrance, refined texture, and non-irritating properties. Demonstrating sustained stability, the formulation underscores its potential as a natural and efficacious cosmetic product. This research adeptly integrates age-old wisdom with contemporary scientific scrutiny, underscoring the relevance of exploring traditional skincare practices in a contemporary context. <strong>Conclusion:</strong> The herbal face pack emerges as a promising solution for fostering luminous and resilient skin through the judicious use of natural constituents.</p> <p><strong>Keywords</strong>: herbal skincare, face pack formulation, natural ingredients, skincare research, traditional practices.</p> 2024-03-11T00:00:00+00:00 Copyright (c) 2024 Navaneeth Krishna B, Gopikrishna U V, Prarthan K N, Subrahmanya Pradeep P, Shreesha Shetty, Kavyashree S, AR SHABARAYA Emerging Frontiers and Future Directions in Nanomedicine: A Comprehensive Review 2024-03-11T17:25:14+00:00 RAMDAS BHAT Himasvi M M Varshini N AR Shabaraya <p>Nanomedicine stands at the forefront of healthcare advancements, leveraging nanotechnology to enhance diagnosis, treatment, and disease prevention. Within this rapidly growing field, nanoparticles exhibit unique traits, such as a notable surface area-to-volume ratio and precise targeting abilities, making them valuable in medical applications. The article delves into diverse types of nanomedicines utilized in the pharmaceutical sector, exploring their potential advantages and examining targeted drug delivery mechanisms. Key breakthroughs, like globally recognized therapies such as Doxil and Abraxane, have emerged from nanomedicine. However, it emphasizes the necessity to address regulatory and ethical considerations to ensure both safety and efficacy. The article sheds light on limitations in targeted drug delivery, including issues like limited drug payload capacity and a lack of specificity, emphasizing the importance of addressing these challenges. Despite hurdles, the future of nanomedicine appears promising, poised to revolutionize personalized medicine, elevate disease detection and treatment, and support tissue regeneration and repair. Integration with artificial intelligence is highlighted as a potential avenue for achieving more precise and efficient drug delivery and disease diagnosis. The article underscores the significance of ongoing investments and collaborations among researchers, healthcare providers, and industry partners to surmount obstacles and unlock the full potential of nanomedicine. In conclusion, nanomedicine stands as a dynamic and promising field with the potential to bring about significant improvements in healthcare outcomes.</p> <p><strong>Keywords:</strong> Nanomedicine, Targeted drug delivery system, Treatment, Healthcare, FDA (food and drug administration).</p> 2024-03-11T00:00:00+00:00 Copyright (c) 2024 Ramdas Bhat, Himasvi MM, Varshini N, AR SHABARAYA