International Journal of Current Research in Physiology and Pharmacology 2023-08-27T06:17:54+00:00 Journal Office Open Journal Systems To evaluate the impact of aspirin in prevention of coronary artery disease in superspeciality hospital Jalandhar Punjab, India 2023-08-27T06:17:53+00:00 Abrar Bashir Malik Mashooq Ahmad Mir Zulfkar Qadrie <p><strong>Introduction:</strong> Coronary artery disease (CAD), a prevalent cardiovascular ailment, arises from the gradual accumulation of fatty deposits, cholesterol, and other substances within the coronary arteries – the blood vessels responsible for supplying oxygen and nutrients to the heart muscle. Aspirin plays a pivotal role in the management of Coronary Artery Disease (CAD) due to its antiplatelet properties. CAD often involves the formation of blood clots within narrowed coronary arteries, potentially leading to heart attacks. Aspirin, a blood-thinning medication, helps prevent clot formation by inhibiting the aggregation of platelets, which are blood cells involved in clotting. <strong>Objective: </strong>The objective of this study was to the impact of aspirin in prevention of coronary artery disease in superspeciality hospital Jalandhar Punjab, India. <strong>Methodology:</strong> The study was conducted in cardiac care unit at Nasa and Hub Superspeciality hospital Jalandhar Punjab and exclusively on patients who presented with any kind of cardiac disorder symptoms. This study was approved by the Ethics committee of Nasa And Hub Superspeciality Hospital. All the subjects have signed the informed consent form. In this study, 200 patients were recruited in NASA AND HUB SUPERSPECIALITY HOSPITAL Jalandhar Punjab from 8<sup>th</sup> june 2022 to 8<sup>th</sup> September 2022. <strong>Results and Discussion:</strong> . In this study population, there were significant differences between male and female concerning cardiovascular risk factors, so cigarette smoking is very prevalent in young group and limited for males. We observed that hypertension and diabetes are present at high level in women than men, and the percentage of hypertension and diabetes increase in both gender with age. In the present study, we examined a representative sample of visits to physicians in the <strong>Nasa And Hub </strong>Superspeciality Hospital by patients with coronary artery disease, with a focus on visits to cardiologists and primary care physicians by patients in whom aspirin was not contraindicated. <strong>Conclusion: </strong>Aspirin continues to be the mainstay of antiplatelet therapy in individuals with coronary artery disease (CAD) in this observational study. Patients at a high risk of developing CVD in the future may be advised to take aspirin, but the potential for adverse effects must be recognised in addition to the advantages. As a result of our study, it is imperative to reinforce the need for proper coronary artery disease (CAD) management in order to prevent further coronary artery complications.</p> <p><strong>Keywords: </strong>Coronary artery disease, aspirin, smoking, hypertension</p> 2023-08-27T00:00:00+00:00 Copyright (c) 2023 Abrar Bashir Malik, Mashooq Ahmad Mir, Zulfkar Qadrie, MOHD ALTAF DAR Reproductive Health of Women: a comprehensive review 2023-08-27T06:17:54+00:00 Imran Gani Irfat Ara Mohd Altaf Dar <p>Full access to sexual and reproductive health is a fundamental human right. Women and girls around the world, especially those living in poverty, have little or no access to reproductive health and rights information and services. Discrimination, shame, restrictive laws and regulations, and long-standing traditions are just some of the existing barriers to sexual and reproductive health. There is evidence that these rights affect not only individual women, but also families, communities and economies, but progress has been slow. Women's lifestyles have evolved throughout history. Life used to be difficult for most women. Many women have had unwanted pregnancies. Childbirth used to be dangerous and often ended in the death of the mother. Most women have never suffered menopause or senility in the past because they did not live long enough. Reproductive health is an important aspect of an individual's overall development and well-being. It may be the result of positive parenting, which is essential in adolescence and lays the foundation for good health in adulthood and beyond reproductive age, in both men and women. Female reproductive life does not begin at puberty and end at menopause. Also, a man's reproductive lifespan doesn't end when he becomes less likely to have more children. It is present and essential at every stage of human development and maturity. Reproductive health needs vary by age and stage of life. However, there are long-term effects throughout life, with each stage having a significant impact on future well-being.</p> <p><strong>Keywords: </strong>Women health, adulthood, fertility, sexual health, menstruation.</p> 2023-08-27T00:00:00+00:00 Copyright (c) 2023 Imran Gani, Irfat Ara, Mohd Altaf Dar